Cristóbal Loézar Hernández


Department of Public Health, School of Medicine, Universidad de Valparaíso, Chile.

Cristóbal Loézar is a surgeon and eye disease specialist at Universidad de Valparaíso. He has a Diploma in Evidence-Based Medicine and in University Teaching for Health Professionals from the Pontificia Universidad Católica de Chile. He also has a Diploma in Research Science and Evidence-Based Medicine from the Universidad de Los Andes. He is currently undertaking the clinical and research fellowship programme in cornea, cataract and ocular surface at Fundación Oftalmológica Los Andes of Universidad de Los Andes. He works as an assistant professor at the Department of Public Health of the School of Medicine of the Universidad de Valparaíso and is a member of the Cochrane Associate Centre of the Universidad de Valparaíso. He conducts research in ophthalmology (anterior segment of the eyeball) and in Evidence-based Health.

Link research



Vargas-Peirano M, Verdejo C, Vergara-Merino L, Loézar C, Hoehmann M, Pérez-Bracchiglione J. Intravitreal antivascular endothelial growth factor in diabetic macular oedema: scoping review of clinical practice guidelines recommendations. Br J Ophthalmol [Internet]. 2021 Dec 14; Available from:

Pérez I, Taito-Vicenti IY, González-Xuriguera CG, Carvajal C, Franco JVA, Loézar C. How to interpret diagnostic tests. Medwave. 2021 Aug 4;21(7):e8432. Spanish, English. doi: 10.5867/medwave.2021.07.8432. PMID: 34369918.

Papuzinski C, Loézar C, Carvajal N, Vargas M, Borgeat M, Madrid E, Perez-Bracchiglione J, Arancibia M Inclusion of evidence-based health in undergraduate programs in Chile and the integrated model Scientific Research Methodology-Evidence-Based Medicine at the University of Valparaíso Educación Médica Volume 22, Supplement 3, June 2021, Pages 179-184

Salas Apaza J, Franco JVA, Meza N, Madrid E, Loézar C, Garegnani L. Minimal Clinically Important Difference: the basics Medwave 2021;21(03):e8149 Doi 10.5867/medwave.2021.03.8149

Schuller B, Meza N, Pérez-Bracchiglione J, Franco JVA, Loézar C, Madrid E. Graphical representation of the body of the evidence: the essentials for understanding the evidence gap map approach. April 2021 Medwave 21(3):e8164 DOI: 10.5867/medwave.2021.03.8164

Tapia-Benavente L, Vergara-Merino L, Garegnani LI, Ortiz-Muñoz L, Loézar Hernández C, Vargas-Peirano M. Rapid reviews: definitions and uses. Medwave. 2021 Jan 5;21(1):e8090. Spanish, English. doi: 10.5867/medwave.2021.01.8090. PMID: 33755038.

Kirmayr M, Quilodrán C, Valente B, Loezar C, Garegnani L, Franco JVA. The GRADE approach, Part 1: how to assess the certainty of the evidence. Medwave. 2021 Mar 17;21(2):e8109. Spanish, English. doi: 10.5867/medwave.2021.02.8109. PMID: 33830974.

Loezar C, Pérez-Bracchiglione J, Arancibia M, Meza N, Vargas M, Papuzinski C, Rada G, Ondarza C, Jahr C, Cadena C, Madrid E. Guidelines in Low and Middle Income Countries Paper 2: Quality assessment of Chilean guidelines: need for improvement in rigor, applicability, updating, and patients’ inclusion. J Clin Epidemiol. 2020 Nov;127:177-183. doi: 10.1016/j.jclinepi.2020.07.018. Epub 2020 Aug 24. PMID: 32853762.

Chamorro F, Briones C, Loezar C, Leon A, Arancibia M, Stojanova J, et al. Corneal endothelial cell loss associated to phacoemulsification and ophthalmologist experience: prospective analysis of individual secondary data. Medwave. 2018 Oct 29;18(6):e7314.

Cristobal Loezar, Eva Madrid, Catalina Jahr, Antonio Daviu, Herman Ahumada, Hector Pardo-Hernandez, Eva Keller, Xavier Bonfill Identification and description of controlled clinical trials published in Spanish Ophthalmology Journals. Ophthalmic Epidemiol. 2018 Dec;25(5–6):436–42 doi: 10.1080/09286586.2018.1503688

Madrid E, Barros Monge MJ, Urrútia G, Roqué i Figuls M, Pérez Bracchiglione J, Vargas Peirano M, Loézar Hernández CN, Bonfill Cosp X. Taxanes for advanced non-small cell lung cancer. Cochrane Database of Systematic Reviews 2018, Issue 7. Art. No.: CD013075. (WOS) . DOI: 14651858.CD013075.