Manuel Vargas Peirano


Department of Public Health, School of Medicine, Universidad de Valparaíso, Chile.

Manuel Vargas graduated as a surgeon specialising in ophthalmology from the Universidad de Valparaíso. He has a Diploma in Medical Education from the Universidad Católica de Chile. He currently works as an assistant professor in the Department of Public Health at the School of Medicine at the University of Valparaíso. Manuel carries out biomedical research in evidence-based health and ophthalmology. He is a researcher at the Centro Interdisciplinario de Estudios en Salud (CIESAL) at the Universidad de Valparaíso and a member of that university’s Cochrane Associate Centre. He is currently leading a research team within the LOVE COVID-19 Working Group, conducting a Living Systematic Review investigating the effects of non-steroidal anti-inflammatory drugs in patients with SARS COV-2.

Link research



Madrid E, Ocara Vargas M, Contreras-Vera C, Saldías C, Escobar Liquitay CM, Novik A V, Munoz SR, Bracchiglione J. Glucagon‐like peptide‐1 analogues for overweight or obese adults. Cochrane Database of Systematic Reviews 2022, Issue 9. Art. No.: CD015092. DOI: 10.1002/14651858.CD015092.

Papuzinski C, Loézar C, Carvajal N, Vargas M, Borgeat M, Madrid E, Perez-Bracchiglione J, Arancibia M Inclusion of evidence-based health in undergraduate programs in Chile and the integrated model Scientific Research Methodology-Evidence-Based Medicine at the University of Valparaíso Educación Médica Volume 22, Supplement 3, June 2021, Pages 179-184

Tapia-Benavente L, Vergara-Merino L, Garegnani LI, Ortiz-Muñoz L, Loézar Hernández C, Vargas-Peirano M. Rapid reviews: definitions and uses. Medwave. 2021 Jan 5;21(1):e8090. Spanish, English. doi: 10.5867/medwave.2021.01.8090. PMID: 33755038.

Vargas-Peirano M, Verdejo C, Vergara-Merino L, Loézar C, Hoehmann M, Pérez-Bracchiglione J. Intravitreal antivascular endothelial growth factor in diabetic macular oedema: scoping review of clinical practice guidelines recommendations. Br J Ophthalmol [Internet]. 2021 Dec 14; Available from:

Verdejo C, Tapia-Benavente L, Schuller-Martínez B, Vergara-Merino L, Vargas-Peirano M, Silva-Dreyer AM. What you need to know about scoping reviews. Medwave 2021;21(02):e8144

Vergara-Merino L, Verdejo C, Carrasco C, Vargas-Peirano M. Living systematic review: new inputs and challenges. Medwave. 2020 Dec 23;20(11):e8092. Spanish, English. doi: 10.5867/medwave.2020.11.8092. PMID: 33382391.

Loezar C, Pérez-Bracchiglione J, Arancibia M, Meza N, Vargas M, Papuzinski C, Rada G, Ondarza C, Jahr C, Cadena C, Madrid E. Guidelines in Low and Middle Income Countries Paper 2: Quality assessment of Chilean guidelines: need for improvement in rigor, applicability, updating, and patients’ inclusion. J Clin Epidemiol. 2020 Nov;127:177-183. doi: 10.1016/j.jclinepi.2020.07.018. Epub 2020 Aug 24. PMID: 32853762.

Urrea G, Llanos P, Meza N, Vargas M, Ortiz-Muñoz L, Rada G, Madrid E Nonsteroidal anti-inflammatory drugs in patients with COVID-19: A living systematic review OSF 2020 DOI: 10.17605/OSF.IO/UYVHA

Vargas-Peirano M, Navarrete P, Diaz T, Iglesias G, Hoehmann M. Care of ophthalmological patients during the COVID-19 pandemic: A rapid scoping review. Medwave. 2020 May 13;20(4):e7902.

Vergara-Merino L, Verdejo C, Carrasco C, Vargas-Peirano M, Living systematic review: new inputs and challenges Medwave 2020;20(11):e8092 doi: 10.5867/medwave.2020.11.8092.

Madrid E, Barros Monge MJ, Urrútia G, Roqué i Figuls M, Pérez Bracchiglione J, Vargas Peirano M, Loézar Hernández CN, Bonfill Cosp X. Taxanes for advanced non-small cell lung cancer. Cochrane Database of Systematic Reviews 2018, Issue 7. Art. No.: CD013075. (WOS) . DOI: 14651858.CD013075.


Minsal ID 757-79-LP21 DIPLAS. Contratación de servicios de búsqueda, extracción de datos, evaluación de riesgo de sesgo y síntesis de evidencia científica para guías de práctica clínica GES (2021-2022) Ministerio de Salud Subsecretaría de Salud Pública SBEETESA. Rol: Coordinadora e investigadora principal.

Solución tecnológica de adaptador para Smartphone y app móvil para el mejoramiento de la toma y registro de examen de retina mediante oftalmoscopía indirecta con teléfono móvil. (2022-2024) Proyecto 100-INES Innova UV.