Nicolás Meza Concha


Researcher at CIESAL.

Nicolás Meza is a graduated general practitioner MD from the Universidad de Valparaíso (Chile) and an Assistant Associate Professor at the Department of Public Health. Currently, he works at the Department of Cardiovascular Diseases at the Medical School of the the Universidad de Valparaíso (Chile).


During his career, he has led different evidence-synthesis projects to inform health-decision making in both local and international settings.


Currently, he is exploring the biostatistical properties of both composite time-to-event and continuous outcomes to measure health-related phenomena—as a PhD student at the Autonomous University of Barcelona. He is also student in the MSc program of Biostatistics and Bioinformatics at the UOC and UB (Spain).


Nicolás is Associate Editor of the BMJ Evidence-Based Medicine.

Link research



Escobar-Liquitay C. Franco J. Bracchiglione J, Meza N, Madrid E Methodological and users’ surveys on the use of Latin American and Caribbean Literature in Health Sciences (LILACS) in Cochrane reviews identified required improvements to this resource.  Health Information and Libraries Journal (In Press).

Mandiola MI, Arancibia M, Elton V, Madrid E, Meza N, Stojanova J, Lutz M, Leyton F. [Perfectionism, academic stress and social anxiety in female medical students and the risk for eating disorders]. Rev Med Chil. 2022 Aug;150(8):1046-1053. doi: 10.4067/S0034-98872022000801046.PMID: 37358152

Bracchiglione J, Meza N, Pérez-Carrasco I, Vergara-Merino L, Madrid E, Urrútia G, Bonfill Cosp X A methodological review finds mismatch between overall and pairwise overlap analysis in a sample of overviews. .J Clin Epidemiol. 2023 May 8;159:31-39. doi: 10.1016/j.jclinepi.2023.05.006. Online ahead of print.PMID: 37164290 Review.

Salazar J, Bracchiglione J, Acosta-Dighero R, Meza N, Meade AG, Quintana MJ, Requeijo C, Rodríguez-Grijalva G, Santero M, Selva A, Solà I, Bonfill X; Systemic oncological treatments in patients with advanced pancreatic cancer: a scoping review and evidence map Appropriateness of Systemic Oncological Treatments for Advanced Cancer (ASTAC) Research Group.Support Care Cancer. 2023 Jan 9;31(2):100. doi: 10.1007/s00520-022-07564-8.PMID: 36622453

Meza N; Rees R; Escobar Liquitay CM; Franco JVA;et al. (1/9). 2022. Atypical antipsychotics for autism spectrum disorder: a network meta-analysis (protocol) Cochrane Database of Systematic Reviews.

Javier Pérez-Bracchiglione; Meza N; Bangdiwala SI; Niño de Guzmán E; Urrútia G; Bonfill X; Madrid E. (2/7). 2022. Graphical Representation of Overlap for OVErviews: GROOVE tool Research Synthesis Methods. Wiley Online Library. early view.

Meza N; Rojas V; Escobar Liquitay CM; et al; Franco JVA. (1/9). 2022. Non-pharmacological interventions for autism spectrum disorder in children: an overview of systematic reviews BMJ Evidence-Based Medicine. BMJ Publishing Group. Online First. ISSN 2515-4478.

Garegnani LI; Meza N; Rosón-Rodríguez P; Escobar Liquitay CM; Arancibia M; Madrid E; Franco JVA. (2/7). 2022. Patients’ participation in government-sponsored guidelines in Latin America: a cross-sectional study BMJ Evidence-Based Medicine. BMJ Publishing Group. 27, pp.21-26. ISSN 2515-4478.

Fieiras C; Chen MH; Escobar Liquitay CM; Meza N; Rojas V; Franco JVA; Madrid E. (4/7). 2022. Risperidone and aripiprazole for autism spectrum disorder in children: an overview of systematic reviews BMJ Evidence-Based Medicine. BMJ Publishing Group. Online First. ISSN 2515-4478.

Meza, Nicolás; P{\’e}rez-Bracchiglione, Javier; P{\’e}rez,Ignacio; Carvajal, Cristhian; Ortiz-Muñoz, Luis; Olgu{\’\i}n, Pablo; Rada, Gabriel; Madrid, Eva. (1/8). 2021. Angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers for COVID-19: a living systematic review of randomized clinical trials Medwave. Medwave. 21-02. Google Scholar (1)

Vergara-Merino, Laura; Meza, Nicolás; Couve-Pérez, Constanza;  Carrasco, Cynthia; Ortiz-Muñoz, Luis; Madrid, Eva; Bohorquez-Blanco, Sandra; Pérez-Bracchiglione, Javier. (2/8). 2021. Maternal and perinatal outcomes related to COVID-19 and pregnancy: an overview of systematic reviews Acta obstetricia et gynecologica Scandinavica. Wiley. 100-7, pp.1200-1218. Google Scholar (19)

Garegnani, Luis Ignacio; Madrid, Eva; Meza, Nicolás (AC). (3/3). 2021. Misleading clinical evidence and systematic reviews on ivermectin for COVID-19 BMJ Evidence-Based Medicine. Royal Society of Medicine. Online First. Google Scholar (23)

Loézar, Cristóbal; Pérez-Bracchiglione, Javier; Arancibia, Marcelo; et al; Meza, Nicolás; Madrid E. (4/11). 2020. Guidelines in low and middle income countries paper 2: Quality assessment of Chilean guidelines:need for improvement in rigor, applicability, updating, and patients’ inclusion Journal of Clinical Epidemiology. Pergamon. 127, pp.177-183. Google Scholar (3)

Olivero, Pablo; Lozano, Carlo; Sotomayor-Zarate, Ramon; et al; Meza-Concha, Nicolás; Marchant, Ivanny. (4/9). 2018. Proteostasis and mitochondrial role on psychiatric and neurodegenerative disorders: current perspectives Neural plasticity. Hindawi. 2018. Google Scholar (16)

Meza-Concha, Nicolás; Arancibia, Marcelo; Salas, Felicia; Behar, Rosa; Salas, German; Silva, Hernan; Escobar, Rocio. (1/7). 2017. Towards a neurobiological understanding of alexithymia Medwave. Medwave. 17-04. Google Scholar (35)

Franco JVA; Dwan K; Garegnani LI; et al; Meza N; Veroniki. (7/11). 2022. Advocating for evidence-informed decisions to make healthcare fit for each person BMJ Evidence-Based Medicine. BMJ Publishing Group. 27, pp.65-66. ISSN 2515-4478.

Franco, Juan Victor Ariel; Meza, Nicolas. (2/2). 2021. Authors should also report the support for judgment when applying AMSTAR 2 Journal of Clinical Epidemiology. Elsevier. 138, pp.240-240. Google Scholar (1)

Schuller-Martínez, Bastián; Meza, Nicolás; Pérez-Bracchiglione, Javier; Franco, Juan Víctor Ariel; Loezar, Cristóbal; Madrid, Eva. (2/6). 2021. Graphical representation of the body of the evidence:the essentials for understanding the evidence gap map approach Medwave. Medwave. 21-03.

González-Xuriguera, Catalina Gracia; Vergara-Merino, Laura; Garegnani, Luis; Ortiz-Múnoz, Luis; Meza, Nicolás. 2021. Introduction to network meta-analysis for evidence synthesis Medwave. Medwave. 21-06.

Salas Apaza, Julieta Aldana; Franco, Juan Victor Ariel; Meza, Nicolás; Madrid, Eva; Loezar, Cristobal; Garegnani, Luis. (3/6). 2021. Minimal clinically important difference: the basics Medwave. Medwave. 21-3. Google Scholar (1)

Meza, Nicolás; Leyton, Fanny.  2021. Vortioxetine for generalised anxiety disorder in adults Medwave. Medwave. 21-03.

Franco, Juan Victor Ariel; Arancibia, Marcelo; Meza, Nicolás; Madrid, Eva; Kopitowski, Karin. (3/5). 2020. Clinical practice guidelines: concepts, limitations and challenges Medwave. Medwave. 20-3. Google Scholar (7)

Verdejo, Catalina; Vergara-Merino, Laura; Meza, Nicolás; Perez-Bracchiglione, Javier; Carvajal-Juliá, Natalia; Madrid, Eva; Rada, Gabriel; Rojas Reyes, María Ximena. (3/8). 2020. Macrolides for the treatment of COVID-19: a living, systematic review Medwave. Medwave. 20-11. Google Scholar (5)

Garegnani, Luis Ignacio; Roson, Pablo; Liquitay, Camila Escobar; Meza, Nicolás; Arancibia, Marcelo; Madrid, Eva; Franco, Juan Victor Ariel. (4/7). 2020. Use of Cochrane reviews in nationally-developed clinical practice guidelines in Latin America Medwave. 20-8, pp.e8027-e8027. Google Scholar (1)

Behar, Rosa; Arancibia, Marcelo; Gaete, Maria Isabel; Silva, Hernan; Meza-Concha, Nicolás. (5/5). 2018. The delusional dimension of anorexia nervosa: phenomenological, neurobiological and clinical perspectives Archives of Clinical Psychiatry. Faculdade de Medicina da Universidade de Sao Paulo. 45, pp.15-21. Google Scholar (7)

Martinez-Aguayo, Juan Carlos; Arancibia, Marcelo; Meza-Concha, Nicolás; Bustamante, Camila; Pérez-Bracchiglione, Javier; Madrid, Eva. (3/5). 2017. Brief psychosis induced by methylphenidate in a child with attention deficit disorder: a case report and literature review Medwave. Medwave. 17-05. Google Scholar (9)

Martinez-Aguayo, Juan Carlos; Middleton, Felipe; Nahuelcura, Katyna; et al; Meza-Concha, Nicolás; Madrid, Eva. (5/5). 2017. Caracterización fenomenológica de las conductas repetitivas impulsivas orientadas hacia el cuerpo y el trastorno por excoriación en estudiantes universitarios Revista chilena de neuro-psiquiatría. Sociedad de Neurología, Psiquiatría y Neurocirugía. 55-4, pp.221-230.

Behar, Rosa; Arancibia, Marcelo; Heitzer, Cristobal; Meza, Nicolás. (4/4). 2016. Trastorno dismórfico corporal: aspectos clínicos, dimensiones nosológicas y controversias con la anorexia nerviosa Revista médica de Chile. Sociedad Médica de Santiago. 144-5, pp.626-633. Google Scholar (25)


Proyecto. 1212037, Mapping of Chilean Clinical Health Research Through a Systematic Approach for Identifying Evidence Gaps: a Step Towards Evidence-Informed Decision Making and Strategic Research Agendas. Agencia Nacional de Investigación y Desarrollo (ANID). Eva Madrid. (Centro Interdisciplinario de Estudios en Salud (CIESAL)). 01/04/2021-

Proyecto. s/n, Commissioned Evidence Synthesis for the Gastroenteritis in Children Guideline project. KSA Task Force. Gabriel Rada. (Epistemonikos Foundation). 01/02/2022-01/05/2022. 19.000 €. Miembro de equipo.

Proyecto. 757-79-LP21, Búsqueda, extracción de datos, evaluación de riesgo de sesgo y síntesis de evidencia científica para guías de práctica clínica GES. Ministerio de Salud (MINSAL). Eva Madrid. (Centro Interdisciplinario de Estudios en Salud (CIESAL)). 01/12/2021-01/05/2022. 21.000 €. Investigador principal.

Proyecto. 757-22-L120, Diseño manual para el abordaje integral de los trastornos del espectro autista en niños y niñas. Ministerio de Salud (MINSAL). Eva Madrid. (Centro Interdisciplinario de Estudios en Salud (CIESAL)). 01/07/2020-01/03/2021. 2.300 €. Miembro de equipo.